WebAbstract A Michael addition-driven four-component reaction (4-CR) was developed for derivatizing chromones by strategically suppressing competing 4-CR Ugi reaction … WebJun 13, 2024 · The chromone and thiochromone scaffolds were designed using disubstituted functional groups. The substitutions were made by using electron-donating groups (EDG) such as amine, hydroxyl, methyl, ether, and ethyl groups and the electron-withdrawing groups (EWG) such as nitro, chlorine, carboxyl, and aldehyde groups.
Recent advances in green synthesis of chromones SpringerLink
Webreaction of the chromone aldehydes 1 and also the retro-aldol reaction of the homoallyl alcohols 2 induced by some nitrogenous nucleophiles. Experimental IR spectra were recorded in KBr on a Beckmann IR 20A instrument, 1H NMR spectra in CDCl 3 on a Bruker 300 MHz spectrometer, mass WebJan 1, 2024 · The catalyst can be re-used for up to four times and showed minimal loss of activity. The ACPs was prepared in a one pot reaction containing chromone based aldehydes, aniline derivatives and diethyl phosphite. The structures of these compounds were characterized by IR, 1 H NMR, 13 C NMR, 31 P NMR and high resolution mass … low graphic requirement games
GB1364262A - Chromone aldehyde derivatives - Google …
WebChromone synthesis via the chalcone pathway. Reagents and conditions: (a) The appropriate isonicotinaldehyde, KOH, EtOH, 50 C rt, overnight. (b) benzaldehyde, KOH, EtOH, 50 C rt, overnight (c) I... WebJul 8, 2011 · The one-pot synthesis of 2-substituted-3-carboxychromones is readily attained by the reaction of 3-oxo-3-(2,6-difluorophenyl)propanoates and acyl chlorides … WebMay 2, 2024 · Chromones constitute an important class of oxygen-containing heterocyclic compounds 1 found to be efficient pharmacophores in some drugs and several flavonoids, such as flavones. 2 These scaffolds are reported to display various pharmaceutical and biological activities including anti-inflammatory, 3 antioxidant, 4 antifungal, 5 antiHIV, 6 … jarod fitzgerald clarkston wa