Biological applications of ionophores

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August undefined, 2024

WebMar 4, 2024 · Cu ionophores include HQs that have a vast variety of biological applications. The most known compound of the HQ class is 7-iodo- 5-chloro-8-hydroxyquinoline (CQ) that was first used as an antibiotic and more recently has been studied for the repurposing in different diseases ranging from neurodegenerative … WebMay 27, 2024 · A comprehensive investigation of the structure-activity relationships, selectivity aspects and biological implications in terms of potential therapeutic applications of these ionophores will be …

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WebMar 4, 2024 · The development of new therapeutic agents should aim to increase selectivity and therefore reduce side effects. In addition, these agents should overcome cancer cell resistance and target cancer ... WebMar 1, 2024 · Herein, the biological applications of Zn ionophores are reviewed, discussing the coordination chemistry, the mechanism of action, and interactions with target … how to sync your time

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WebBiological applications of ionophores. Pressman BC. Annual Review of Biochemistry , 01 Jan 1976, 45: 501-530 DOI: 10.1146 ... Biological applications and evolutionary origins of ionophores. Pressman BC, deGuzman NT. Adv Exp Med Biol, 84:285-300, 01 Jan 1977 WebJul 1, 1976 · Ionophores are compounds of moderate molecular weight (about 200-2(00) that form lipid-soluble complexes with polar cations, of which K+, Na+, Ca2+, Mg2+, and … WebNov 1, 2024 · Cu ionophores include HQs that have a vast variety of biological applications. The most known compound of the HQ class is 7-iodo-5-chloro-8-hydroxyquinoline (CQ) that was first used as an ... how to sync zimbra calendar with outlook

Frontiers Selective Targeting of Cancer Cells by Copper Ionophores ...

Comparison of the Activity of Ionophores with Other Antibacterial ...

WebFeb 12, 2024 · Ion-selective electrodes (ISEs) are one of the most established types of chemical sensors, commercialized for a wide variety of applications ranging from their use as indicator electrodes in titrations to the direct determination of ions in clinical analysis. 1 This latter application has been largely aided by the implementation of ionophore-based … WebThe control of ion transport and homeostasis is a critical function of living organisms. In this perspective, an overview of different synthetic systems capable of facilitating the transmembrane transport of ions along with the biological activity exerted by these compounds is presented. Examples of both cat reads ifmltd.comWebJan 15, 2000 · Monopodal and oligopodal Mg2+-selective ionophores were characterized by their selectivity coefficients (Separate Solution Method, SSM) in plasticized poly ... “Chemical Sensors and Biosensors for Medical and Biological Applications”, 1998, Wiley–VCH, Weinheim. M. Müller, M. Rouilly, B. Rusterholz, M. Maj-Zurawska, Z. Hu, … how to sync zoho calendar with outlook

"WebIonophores transport ions across biological membranes and have wide-ranging applications, but a platform for their rapid development does not exist. We report a platform for developing ionophores from metal-ion chelators, which are readily available with wide-ranging affinities and specificities, and structural data that can aid rational design. " - Biological applications of ionophores

Biological applications of ionophores

WebOct 9, 2016 · Biological applications of ionophores. Annu Rev Biochem. 1976; 45:501–530. [Google Scholar] Reiner R, Weiss U, Brombacher U, Lanz P, Montavon M, Furlenmeier A, Angehrn P, Probst PJ. Ro 13-9904/001, a novel potent and long-acting parenteral cephalosporin. J ... WebMay 27, 2024 · Despite several ionophores revealing potential therapeutic applications as apoptosis inducers, ... In the context of transporting molecules of biological relevance, quite a few ionophores have been …

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In chemistry, an ionophore (from Greek ion and -phore 'ion carrier') is a chemical species that reversibly binds ions. Many ionophores are lipid-soluble entities that transport ions across the cell membrane. Ionophores catalyze ion transport across hydrophobic membranes, such as liquid polymeric membranes (carrier-based ion selective electrodes) or lipid bilayers found in the living cells or synthetic vesicles (liposomes). Structurally, an ionophore contains a hydrophilic center … WebIonophores are compounds that form lipid soluble, dynamically reversible complexes with cations and by this means facilitate specific ionic transport across biologic membranes (Pressman, 1976; Reed, 1982; Taylor et al., 1982 ). There are two major subclasses of ionophores, (1) neutral ionophores, which are highly toxic because they form charged ...

WebIonophores are a class of compounds that form complexes with specific ions and facilitate their transport across cell membranes. An ionophore typically has a hydrophilic pocket (or hole) that forms a binding site specific for a particular ion. The exterior surface of an ionophore is hydrophobic, allowing the complexed ion in its pocket to cross the … WebBiological applications and evolutionary origins of ionophores. Pressman BC , deGuzman NT Adv Exp Med Biol, 84:285-300, 01 Jan 1977 Cited by: 6 articles PMID: …

WebThe Hippo pathway was initially discovered in Drosophila melanogaster as a key regulator of tissue growth. It is an evolutionarily conserved signaling cascade regulating numerous … WebAs it has turned out, medical and pharmaceutical applications of ionophores are limited, since the activity of ionophores is not restricted to microbial membranes. On the other hand, ionophores were found to be wonderful tools in biochemical research at the cellular or membrane level. ... Pressman, B.C.: Biological applications of ionophores ...

WebAnalogous ionophores have now been synthesized. Unique applications for these compounds are emerging, based either on their selective toxicity or ability to modify …

WebPolyether ionophores are complex natural products capable of transporting cations across biological membranes. Many polyether ionophores possess potent antimicrobial activity and a few selected compounds have the ability to target aggressive cancer cells. Nevertheless, ionophore function is believed … how to sync your laptop to your smart tvWebApr 6, 2024 · Ionophores transport ions across biological membranes and have wide-ranging applications, but a platform for their rapid development does not exist. We report a platform for developing ionophores from metal-ion chelators, which are readily available with wide-ranging affinities and specificities, and structural data that can aid rational design. how to sync your music library reads hyundai bostonWebDec 21, 2024 · Zinc ionophores increase the intracellular concentration of Zinc ions causing significant biological effects. This review provides, for the first time, an overview of the … how to sync zoho books with hdfc bankWebThe control of ion transport and homeostasis is a critical function of living organisms. In this perspective, an overview of different synthetic systems capable of facilitating the … reads high or low from a pinWebJan 1, 2024 · Biological Applications of Ionophores. Article. Feb 1976; Berton C. Pressman; View. Effects of a low protein diet during pregnancy of the rhesus monkey. I. Reproductive efficiency. Article. how to synchronize chimes on mantel clockWebApr 13, 2024 · Matthew Songer, (Biological Sciences ’79) and Laura Songer (Biological Sciences ’80) have generously donated funds to the College of Sciences and Arts (CSA) … how to synchronize christmas lights to music